Vascular cognitive impairment neuropathology guidelines (VCING): the contribution of cerebrovascular pathology to cognitive impairment

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Vascular cognitive impairment neuropathology guidelines (VCING): the contribution of cerebrovascular pathology to cognitive impairment.

There are no generally accepted protocols for post-mortem assessment in cases of suspected vascular cognitive impairment. Neuropathologists from seven UK centres have collaborated in the development of a set of vascular cognitive impairment neuropathology guidelines (VCING), representing a validated consensus approach to the post-mortem assessment and scoring of cerebrovascular disease in relat...

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BACKGROUND AND PURPOSE Besides cerebrovascular disease, medial temporal lobe atrophy (MTA), a neuroimaging finding suggestive of degenerative pathology, has been shown in vascular dementia (VaD). However, it is unknown to what extent MTA contributes to the pattern of cognitive impairment observed in VaD. Therefore, our purpose was to investigate the relative contribution of cerebrovascular dise...

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Vascular cognitive impairment.

Dementia, a syndrome of declining higher cognitive functioning, found in approximately 10 per cent of adults 65 years and older, and 50 per cent of adults older than 90 years. Alzheimer’s disease (AD) accounts for 50 to 80 per cent of all dementing illnesses. Vascular dementia comprises 15 to 20 per cent of dementia and in some clinico-pathological series is the second commonest form of dementi...

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Vascular Cognitive Impairment.

Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both. Vascular cognitive impairment refers to all forms of cognitive disorder associated with cerebrovascular disease, regardless of the specific mechanisms involved. It encompasses the full range of cognitive deficits from mild cognitive impairment to dementia. In principle, any of the multiple causes of clinical...

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ژورنال

عنوان ژورنال: Brain

سال: 2016

ISSN: 0006-8950,1460-2156

DOI: 10.1093/brain/aww214